Mbeya is one of Tanzania's 26 administrative regions. The regional capital is Mbeya. It is bordered to the northwest by Tabora Region, to the northeast by Singida Region, to the East by Iringa Region, to the South by Zambia and Malawi and to the West by Rukwa Region. Mbeya Region is occupied by several different ethnic groups including the Nyakyusa, Ndali, Nyiha, Nyamwanga, Safwa, Malila, Vwanji (or Wanji), Bungu, Sangu, Wanda and Sichela.
According to the 2002 Tanzania National Census, the population of the Mbeya Region was 2,070,046.
The Regional Commissioner for the Mbeya Region is Mateo Quaresi.
The Mbeya Regions is administratively divided into 8 districts: Chunya, Mbarali, Mbozi, Rungwe, Kyela, Ileje, Mbeya Urban and Mbeya Rural.